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Skin folds or skinfolds are areas of skin that are naturally folded. Many skin folds are distinct, heritable anatomical features, and may be used for identification of animal species, while others are non-specific and may be produced either by individual development of an organism or by arbitrary application of force to skin, either by the actions of the of the body or by external force, e.g., gravity. Anatomical folds can also be found in other structures and tissues besides the skin, such as the ileocecal fold beneath the terminal ileum of the cecum.
Skin folds are of interest for cosmetology, as some kinds may be considered aesthetically undesirable, and for medicine, because some of them are susceptible to inflammation and infection.
In the literature, when referring to a skin crease, there is variation of terms used other than "crease", such as "fold" and "sulcus", but these terms do not accurately reflect their histology structure nor their function. In the review of literature, a record of the creases of the human body for each anatomic area, including the synonyms that are used for each crease in the literature, has been attempted.
The skin crease as a fixed and permanent line, according to their histology, is related to connective tissue attachments with the underlying structures or extensions of the underlying muscle fibers in the dermis of the crease site.
The skin fold is characterized by skin redundancy that is responsible partly, often in combination with connective tissue attachments, for the skin crease. It is essential to use appropriate terms that accurately reflect the anatomic structure and histology when referring to the skin lines.Mallouris, A., Yiacoumettis, A., Thomaidis, V., Karayiannakis, A., Simopoulos, C., Kakagia, D., & Tsaroucha, A. K. (2012). A record of skin creases and folds. European Journal of Plastic Surgery. 35 (12): 847-854. Cosmo, L. L. (2017). Filling the Gap: on the New Micro-toponomic Phenomena and Partial Topologies. Health Research. 1 (1): 39-49. doi: 10.31058/j.hr.2017.11004
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